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Monday, October 1, 2012
Melatonin and exercise work against Alzheimer's in mice | Science Codex
Melatonin and exercise work against Alzheimer's in mice | Science Codex: The combination of two neuroprotective therapies, voluntary physical exercise, and the daily intake of melatonin has been shown to have a synergistic effect against brain deterioration in rodents with three different mutations of Alzheimer's disease.A study carried out by a group of researchers from the Barcelona Biomedical Research Institute (IIBB), in collaboration with the University of Granada and the Autonomous University of Barcelona, shows the combined effect of neuroprotective therapies against Alzheimer's in mice.
Cancer Drugs Reverse Memory Loss in Alzheimer’s Disease
GEN | News Highlights:Cancer Drugs Reverse Memory Loss in Alzheimer’s Disease: Scientists have made the unexpected discovery that two marketed anticancer drugs can dramatically restore memory in animal models of Alzheimer’s disease (AD), and may feasibly help hold back or even reverse memory loss in human AD patients.
The discovery, by researchers at Cold Spring Harbor Laboratory (CSHL) and Tsinghua University in Beijing (China), was based on studies in a fruit fly model of AD that expresses Aβ42. Yi Zhong, Ph.D., and colleagues found that Aβ42 directly activates EGFR in the brain, and that treating the AD model fruit flies with either of the EGFR inhibitors gefitinib or erlotinib reversed the memory loss that is characteristic of their AD phenotype.
The discovery, by researchers at Cold Spring Harbor Laboratory (CSHL) and Tsinghua University in Beijing (China), was based on studies in a fruit fly model of AD that expresses Aβ42. Yi Zhong, Ph.D., and colleagues found that Aβ42 directly activates EGFR in the brain, and that treating the AD model fruit flies with either of the EGFR inhibitors gefitinib or erlotinib reversed the memory loss that is characteristic of their AD phenotype.
Alzheimer's May be Caused by Poor Diet
foodconsumer.org - Alzheimer's May be Caused by Poor Diet: Can You Eat Your Way to Alzheimer's?
In a recent animal study, researchers from Brown University in Providence, Rhode Island were able to induce many of the characteristic brain changes seen with Alzheimer's disease (disorientation, confusion, inability to learn and remember) by interfering with insulin signaling in their brains.1
Faulty insulin (and leptin, another hormone) signaling is an underlying cause of insulin resistance, which, of course, typically leads to type 2 diabetes. However, while insulin is usually associated with its role in keeping your blood sugar levels in a healthy range, it also plays a role in brain signaling. When researchers disrupted the proper signaling of insulin in the brain, it resulted in dementia.
In a recent animal study, researchers from Brown University in Providence, Rhode Island were able to induce many of the characteristic brain changes seen with Alzheimer's disease (disorientation, confusion, inability to learn and remember) by interfering with insulin signaling in their brains.1
Faulty insulin (and leptin, another hormone) signaling is an underlying cause of insulin resistance, which, of course, typically leads to type 2 diabetes. However, while insulin is usually associated with its role in keeping your blood sugar levels in a healthy range, it also plays a role in brain signaling. When researchers disrupted the proper signaling of insulin in the brain, it resulted in dementia.
Friday, September 28, 2012
Alzheimer’s disease = type 3 diabetes? Maybe
Blogs - Fayobserver.com - Alzheimer’s disease = type 3 diabetes? Maybe: What’s new is the thought that while diabetes doesn’t “cause” Alzheimer’s, they have the same root: an over consumption of those “foods” that mess with insulin’s many roles. (Genetics have an effect on susceptibility, as they appear to with all environmental diseases.) “Sugar is clearly implicated,” says Dr. de la Monte, “but there could be other factors as well, including nitrates in food.”
Adult stem cells can prevent Alzheimer's disease
Adult stem cells can prevent Alzheimer's disease: In the first study of its kind, researchers at Korea's leading university and the RNL Bio Stem Cell Technology Institute announced this week the results of a study that suggests an astounding possibility: adult stem cells may not only have a positive effect on those suffering from Alzheimer's disease, they can prevent the disease. Using fat-derived adult stem cells from humans [scientific term: adMSCs, or human, adipose-derived mesenchymal stem cells], researchers were able to cause Alzheimer's disease brains in animal models to regenerate. The researchers, for the first time in history, used stem cells to identify the mechanism that is key to treatment of Alzheimer's disease, and demonstrated how to achieve efficacy as well as prevention of the symptoms of Alzheimer's with adult stem cells, a "holy grail" of biomedical scientists for decades.
Thursday, September 20, 2012
Margarine: Does it Cause Alzheimer's?
Margarine: Does it Cause Alzheimer's?: A shocking new study in the scientific journal Chemical Research found that an ingredient in margarine intensifies the damaging effect of an abnormal brain protein linked to Alzheimer's. The ingredient is called diacetyl, and it is also commonly used in microwave popcorn, candies, and baked goods. Since margarine has already fallen out of favor among health experts in recent years, should we eliminate it completely from our diets?
Thursday, September 13, 2012
Vitamin C and Beta-Carotene Might Protect Against Alzheimer’s |
Vitamin C and Beta-Carotene Might Protect Against Alzheimer’s | Psych Central News: Researchers have found that the antioxidants vitamin C and beta-carotene are significantly lower in patients with mild dementia, leading to suggestions that it might be possible to influence the progress of Alzheimer’s disease through diet
Some Blood Pressure Drugs Might Help Slow Alzheimer's: Study
Some Blood Pressure Drugs Might Help Slow Alzheimer's: Study - US News and World Report: Angiotensin receptor blockers, drugs commonly taken to control high blood pressure, appear to reduce the amount of plaque in the brains of Alzheimer's patients and others, a new study shows.
These results were found when patients with high blood pressure on drugs such as losartan (Cozaar) died and underwent an autopsy. These brain plaques are a hallmark of Alzheimer's disease. Whether, however, these drug also improve mental function isn't known, the researchers added.
These results were found when patients with high blood pressure on drugs such as losartan (Cozaar) died and underwent an autopsy. These brain plaques are a hallmark of Alzheimer's disease. Whether, however, these drug also improve mental function isn't known, the researchers added.
University Of Ulster News Release - Breakthrough in Alzheimer's Research
University Of Ulster News Release - Breakthrough in Alzheimer's Research: A drug used by diabetes sufferers could have the potential to treat neurodegenerative diseases like Alzheimer’s, a study by scientists at the University of Ulster has revealed.
Type II diabetes is a known risk factor for Alzheimer’s and it is thought that impaired insulin signalling in the brain could damage nerve cells and contribute to the disease.
Scientists believe that drugs designed to tackle Type II diabetes could also have benefits for keeping our brain cells healthy.
Type II diabetes is a known risk factor for Alzheimer’s and it is thought that impaired insulin signalling in the brain could damage nerve cells and contribute to the disease.
Scientists believe that drugs designed to tackle Type II diabetes could also have benefits for keeping our brain cells healthy.
Friday, August 31, 2012
Coco Oil Good Vs Alzheimer’s |
Coco Oil Good Vs Alzheimer’s | : The results of a clinical study undertaken by Dr. Suzanne de la Monte of Rhode Island Hospital and published recently in the Journal of Alzheimer’s disease have created quite a stir at the Philippine Coconut Authority (PCA), which is now poised to support a campaign to promote both coconut oil and coconut sap sugar as a one-two punch against the ailment.
De la Monte’s study, PCA administrator Euclides G. Forbes said, demonstrated that consuming more saturated fats like coconut oil helps reduce the inflammation in the brain that promotes the progression of Alzheimer’s disease
De la Monte’s study, PCA administrator Euclides G. Forbes said, demonstrated that consuming more saturated fats like coconut oil helps reduce the inflammation in the brain that promotes the progression of Alzheimer’s disease
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