Wednesday, June 4, 2014
Breakthrough in Alzheimer's Disease: AFFiRiS Halted Clinical Progression in Alzheimer Patients Upon Treatment With AD04 in a Phase II Clinical Study - MarketWatch
Breakthrough in Alzheimer's Disease: AFFiRiS Halted Clinical Progression in Alzheimer Patients Upon Treatment With AD04 in a Phase II Clinical Study - MarketWatch: AFFiRiS announced today the results of a phase II study in Alzheimer patients. AFFiRiS' proprietary compound AD04 is the first drug ever to demonstrate clinical and biomarker effects consistent with disease modification in Alzheimer patients. Upon treatment with AD04, effects consistent with disease modification were achieved for at least 18 months in 47% of treated patients. This beneficial effect was dose dependent and more effective in early disease patients. Furthermore, prevention of hippocampal decline was correlated with the beneficial impact on clinical progression and was statistically significant. Therefore, these results for the very first time meet all of the criteria for disease modification as defined by US and European Regulatory Agencies FDA (Food and Drug administration) and EMA (European Medicines Agency).
A Word from Dr. Pfenninger: Seven risk factors for Alzheimer's disease
A Word from Dr. Pfenninger: Seven risk factors for Alzheimer's disease: Each time something like this happens to us, especially as we add on a few years in our life, the thought remotely crosses through our minds that perhaps we are getting Alzheimer’s disease (AD). Okay, so maybe it doesn’t happen all the time, but in a busy, active life there are many decisions made every day and things need to be remembered that we forget. When we can’t remember all 102 items, we become concerned.
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