New drug target identified for multiple sclerosis and Alzheimer's disease

New drug target identified for multiple sclerosis and Alzheimer's disease: Researchers at Boston University School of Medicine (BUSM) led by Carmela Abraham, PhD, professor of biochemistry, along with Cidi Chen, PhD, and other collaborators, report that the protein Klotho plays an important role in the health of myelin, the insulating material allowing for the rapid communication between nerve cells. These findings, which appear online in Journal of Neuroscience, may lead to new therapies for multiple sclerosis (MS) and Alzheimer's disease (AD), in which white matter abnormalities are also common but have been largely ignored.

Brain Boosting Tips to Help Prevent Alzheimer’s Disease | fox4kc.com – Kansas City news & weather from WDAF TV – FOX 4

Brain Boosting Tips to Help Prevent Alzheimer’s Disease | fox4kc.com – Kansas City news & weather from WDAF TV – FOX 4: The four main components for Dr. Small’s program are:
1) Physical exercise
2) Healthy diet
3) Mental workouts
4) Reduce your stress

MPL Vaccine Could Treat, Prevent Alzheimer's Disease in Humans

DailyTech - MPL Vaccine Could Treat, Prevent Alzheimer's Disease in Humans: Canadian researchers have come one giant step closer to finding treatment for those with Alzheimer's disease, and even a preventative vaccine.

Exercise and Weight Loss Give Brain a Boost, Study Finds - US News and World Report

Exercise and Weight Loss Give Brain a Boost, Study Finds - US News and World Report: follow-up testing showed that the participants' brain function had also improved, and that the increases were proportional to the improvements in exercise capacity and body weight. Simply put, the more they could exercise and the more weight they had lost, the greater their improvement in thinking skills, the investigators found.

Miracle Molecule Reverses Alzheimer's and Restores Memory in Mice : Science/Tech : Medical Daily

Miracle Molecule Reverses Alzheimer's and Restores Memory in Mice : Science/Tech : Medical Daily: One group of mice was injected with TFP5, while the other was injected with a saline placebo. After receiving the injection of TFP5, the mice's symptoms drastically reduced by 70 to 80 percent and they exhibited improved memory. The injection also did not appear to cause any adverse effects, like weight loss, anxiety or signs of toxicity. On the other hand, the mice that were injected with the placebo degenerated as usual.

Poor Semantic Processing Ability Could Be Early Sign of Alzheimer's Disease : Conditions : Medical Daily

Poor Semantic Processing Ability Could Be Early Sign of Alzheimer's Disease : Conditions : Medical Daily: According to the study authors, previous research on mild cognitive impairment (MCI), an early sign of Alzheimer's diseases, focused mainly on short-term memory loss. However, people might begin losing the ability to recognize size and shapes - which requires some degree of knowledge - before memory related problems kick in.

NLRP3 is activated in Alzheimer/'s disease and contributes to pathology in APP/PS1 mice : Nature : Nature Publishing Group

NLRP3 is activated in Alzheimer/'s disease and contributes to pathology in APP/PS1 mice : Nature : Nature Publishing Group: Deposition of amyloid-β peptide drives cerebral neuroinflammation by activating microglia1, 2. Indeed, amyloid-β activation of the NLRP3 inflammasome in microglia is fundamental for interleukin-1β maturation and subsequent inflammatory events3. However, it remains unknown whether NLRP3 activation contributes to Alzheimer’s disease in vivo.

Alzheimer’s affects men, women differently, researcher finds – The Post and Courier

Alzheimer’s affects men, women differently, researcher finds – The Post and Courier: The study found that in the year leading up to an Alzheimer’s diagnosis women had significantly more brain atrophy, or wasting away. It also discovered that the shrinkage happened in different areas of the brain for men and women.

Statins Against Alzheimer’s Disease | Brain Blogger

Statins Against Alzheimer’s Disease | Brain Blogger: Taking into account the association between high plasma cholesterol and AD, Tramontine and colleagues recently conducted a study to explore the role of statins — a class of lipid-lowering drugs — in the protection against the disease. Although the positive effects of statins on cardiovascular diseases are well known, their potential neuroprotective effects demand further characterization.

Alzheimer's Disease Early Cognitive Problems Identified

Alzheimer's Disease Early Cognitive Problems Identified: The study is the first of its kind to review mild cognitive impairment (MCI) associated with Alzheimer's disease in a systematic way and reveal the early indicators, signs and symptoms. Terry Goldberg, PhD, director of neurocognition at the Litwin Zucker Center for Research in Alzheimer's Disease, and his colleagues developed a test to identify any problems with a person's ability to process semantic or knowledge based information.

Elderly Depression Linked To Dementia Risk And Mild Cognitive Impairment

Elderly Depression Linked To Dementia Risk And Mild Cognitive Impairment: According to the researchers, studies have indicated that from 3% to 63% of patients with MCI have depressive symptoms. Other studies have demonstrated that people with a history of depression have a higher risk of dementia during their later years. A study published in Archives of Neurology in May 2011 revealed that mild cognitive impairment and dementia are much more common among very old women.

7 foods destroying your good mood | Fox News

7 foods destroying your good mood | Fox News: A delightfully toasted sesame seed bagel. Crispy, crunchy potato chips. An effervescent fountain of sweet soda. These all sound like comforting foods that can wrap you in a sensation of coziness. However, while they may taste so good, these foods are not always so good for you or your mood.