Tuesday, July 27, 2010

Eisai May Start Skin-Patch Aricept U.S. Sales in 2011 - Bloomberg

Eisai May Start Skin-Patch Aricept U.S. Sales in 2011 - Bloomberg: "Teikoku Seiyaku Co., Eisai’s development partner, submitted patient-trial data to the U.S. Food and Drug Administration on June 30, Lynn Kramer, head of neuroscience product development at the Tokyo-based company, said on a conference call today. The regulator typically takes 10 months to complete a review."

Proteins linked to longevity also linked to Alzheimer's

Proteins linked to longevity also linked to Alzheimer's: "The finding, reported in the July 23 issue of Cell, suggests that targeting sirtuins could offer a promising new approach to treating Alzheimer’s, says Professor Leonard Guarente, leader of the research team."

More Education Delays Dementia Signs--But Not Damage: Scientific American

More Education Delays Dementia Signs--But Not Damage: Scientific American: "Most of the previous studies describing the link between education and risk for dementia were purely observational—a method in which 'you can't really prove a cause and effect,' says P. Murali Doraiswamy, head of biological psychiatry at Duke University and who was not involved in the new research. He also notes that many of the cognitive tests to diagnose dementia are biased against those who have lower levels of verbal and reasoning abilities due to less education to begin with."

Monday, July 26, 2010

Branded - Drug Store News

Branded - Drug Store News: "The FDA approved Aricept (donepezil hydrochloride) tablets in the 23-mg strength as a once-daily treatment for moderate-to-severe Alzheimer’s. The drug is designed for patients to start off with 5 mg once a day, increasing dosage to 10 mg after four to six weeks and to 23 mg after three more months."

Biologist cites progress on Alzheimer’s - The Boston Globe

Biologist cites progress on Alzheimer’s - The Boston Globe: "A leading antiaging researcher, Leonard Guarente, believes he has found a potential new approach for treating Alzheimer’s disease.
Tweet Submit to DiggdiggsdiggYahoo! Buzz ShareThis For more than 15 years, the MIT biology professor has been researching proteins called sirtuins, which slow an animal’s aging clock during times of scarcity — stalling the animal at a younger and more fertile stage until food becomes more plentiful and reproductive success is more likely."

Friday, July 23, 2010

Alzheimer's breakthrough could lead to treatment - ABC News (Australian Broadcasting Corporation)

Alzheimer's breakthrough could lead to treatment - ABC News (Australian Broadcasting Corporation): "Researchers at the University of Sydney claim a breakthrough in research into Alzheimer's disease will lead directly to a new treatment.
Their study shows how two key proteins interact to trigger the brain degeneration known as Alzheimer's."

Thursday, July 22, 2010

Diet and Behavior Changes May Slow Alzheimer’s - US News and World Report

Diet and Behavior Changes May Slow Alzheimer’s - US News and World Report: "A combination of diet and lifestyle changes decreases Alzheimer’s-like symptoms in dogs more than either treatment does on its own, a new study shows. The findings show the importance of taking multiple approaches to arrest the disease in humans, the authors say. Their results also provide evidence supporting recent research that suggests plaque deposits in the brain are not the cause of Alzheimer’s."

Depression may increase Alzheimer's risk - Technology & science - Science - LiveScience - msnbc.com

Depression may increase Alzheimer's risk - Technology & science - Science - LiveScience - msnbc.com: "As if depression wasn't bad enough on its own, new research suggests older adults with depressive symptoms are at increased risk of developing Alzheimer's disease.
Alzheimer's is a fatal brain disorder marked by memory loss and an inability to function in daily life. Researchers have long known that depression and Alzheimer's disease are linked, but it wasn't clear whether depression was a risk factor for Alzheimer's or a symptom of the disease"

Monday, July 19, 2010

Drug Trials Test Bold Plan to Slow Alzheimer’s - NYTimes.com

Drug Trials Test Bold Plan to Slow Alzheimer’s - NYTimes.com: "The disease is defined by freckles of barnacle-like piles of a protein fragment, amyloid beta, in the brain. So, the current thinking goes, if you block amyloid formation or get rid of amyloid accumulations — plaque — and if you start treatment before the disease is well under way, you might have a chance to alter its course."

Friday, July 16, 2010

Sniffing insulin may help memory lost to Alzheimer's | Reuters

Sniffing insulin may help memory lost to Alzheimer's | Reuters: "(Reuters) - Squirting insulin up the noses of patients with early forms of Alzheimer's disease showed signs of improving their memory, U.S. researchers said on Wednesday.
Patients who got the treatment for four months showed improvements in tests of memory recall that lasted for two months."


DON'T DO THIS ON YOUR OWN

A Scary Idea: Pre-emptive Brain Scans For Alzheimer’s. « The Science Business - Forbes.com

A Scary Idea: Pre-emptive Brain Scans For Alzheimer’s. « The Science Business - Forbes.com: "You feel fine and have no symptoms, but your brain is slowly rotting away. And there is nothing we can do about it. Have a nice day.”
This is what you could be hearing from your doctor in a few years if new “preclinical” Alzheimer’s disease diagnosis recommended by top experts takes hold. Arguing that 'it is widely acknowledged that symptoms are not necessary to diagnose human disease,' an expert panel is proposing creating a strange new category of preclinical Alzheimer's disease that could be diagnosed in totally healthy people, years before there are symptoms."

Thursday, July 15, 2010

5 signs of Alzheimer's | abc7chicago.com

5 signs of Alzheimer's | abc7chicago.com: "WARNING SIGNS OF ALZHEIMERS: In the daily blog of Dr. Andrew Weil, M.D., Dr. Weil notes the five main warning signs of Alzheimer's. The first and most important warning sign is memory loss, such as forgetting important dates and recently learned information. The second most common warning sign is challenges when trying to solve a problem. The third warning sign is when familiar tasks start becoming unfamiliar. In this case, routine tasks such as remembering how to get to get to a certain location or remembering phone numbers becomes difficult. The fourth warning sign is being confused about time and location. The fifth and final most important warning sign for the onset of Alzheimer's is trouble understanding pictures and other visual images. It is at this point that colors seem non-existent and the ability to differentiate between distance and physical objects becomes intricate."

Extra weight can increase risk of Alzheimer’s disease for women : dBTechno

Extra weight can increase risk of Alzheimer’s disease for women : dBTechno: "Results of a new interesting study suggest that the more weight a woman is carrying, the greater their risk is of developing memory loss.
For years researchers have been trying to find clues that would indicate memory loss which can lead to Alzheimer’s disease and now they have found what they say is a key contributor."

Wednesday, July 14, 2010

New Recommendations for Alzheimer's Diagnosis

New Recommendations for Alzheimer's Diagnosis: "July 13, 2010 -- Experts from the National Institute on Aging and the Alzheimer's Association have issued suggestions to update the criteria for the diagnosis of Alzheimer's disease.
The new proposed criteria will be the first update in 26 years.
''The last set of criteria for Alzheimer's disease [diagnosis] were originally developed in 1984,' says William Thies, PhD, chief medical and scientific officer at the Alzheimer's Association. 'We know a lot more now than we did before, so the new criteria are a reaction to that knowledge,' he tells WebMD."

Thursday, July 8, 2010

Vitamin E Reduces Alzheimer's Risk

Vitamin E Reduces Alzheimer's Risk: "High levels of vitamin E in the blood reduce the risk of developing Alzheimer's disease in old age, says a new study. Italian and Swedish researchers found that several components of vitamin E helped prevent cognitive deterioration in people 80 years of age and older.
'Vitamin E is a family of eight natural components, but most studies related to Alzheimer's disease investigate only one of these components, tocopherol,' Dr. Francesca Mangialasche, who led the study, said in a statement. 'We hypothesized that all the vitamin E family members could be important in protecting against AD. If confirmed, this result has implications for both individuals and society, as 70 percent of all dementia cases in the general population occur in people more than 75 years of age, and the study suggests a protective effect of vitamin E against AD in individuals aged 80 plus.'"

CBC News - Technology & Science - Neuron research may hold hope for Alzheimer's

CBC News - Technology & Science - Neuron research may hold hope for Alzheimer's: "U.S. scientists have found a chemical that can form neurons in brains of mice, and improve the memory of old rats.
The results, to be published in the journal Cell on Thursday, offer hope for a cure 'that will address the core illness process in Alzheimer's disease,' said Dr.Thomas Insel, director of the U.S. National Institute of Mental Health (NIMH).
The researchers found a chemical they called P7C3, which supported the formation of neurons — a process called neurogenesis — in the dentate gyrus region of the brain in mice."

Saturday, July 3, 2010

Portals | Molecular Imaging

Portals Molecular Imaging: "Noninvasive retinal imaging may be helpful in the early diagnosis, intervention and monitoring of Alzheimer’s disease (AD), as the beta-amyloid (AB) plaques characteristic of the disease first appear in the eyes, according to a study published online June 13 in NeuroImage."

Thursday, July 1, 2010

Sponsors to Share Trial Data to Develop Alzheimer’s Drugs

Sponsors to Share Trial Data to Develop Alzheimer’s Drugs: "FDAnews Drug Daily Bulletin
June 29, 2010 Vol. 7 No. 126



Sponsors to Share Trial Data to Develop Alzheimer’s Drugs
In a move that could foster faster development of drugs to treat neurodegenerative diseases, a consortium of drugmakers has agreed to share data from Alzheimer’s trials in a new database. The creation of the database is the first effort of its kind to pool industry data to accelerate development of treatments for brain diseases, the Coalition Against Major Diseases says. The database will allow researchers to design better clinical trials and improve chances of success."

Drugs that cure alzheimer's

While it's great to have hope.  Be careful about people that say there's almost a cure.  Perhaps there is; but there have been an awful lot of let downs and research gone awry.  Focus on prevention.  Hope and pray for a cure.

An Alzheimer's cure could be closer than we think | ZDNet

An Alzheimer's cure could be closer than we think ZDNet: "An Alzheimer's cure could be closer than we think
By Dana Blankenhorn June 30, 2010, 9:36am PDT
Summary
Chain has what he calls a “platform” covering at least three monoclonal antibodies that can act against Alzheimer’s. One drug based on the platform is in a Stage Three trial. Others are in first or second stage trial.
Topics
Alzheimer's Disease, Dana Blankenhorn
I have written about Alzheimer’s disease several times on this blog.
Alzheimer’s is the mind stealer, a terribly long, sad fade-out. My grandfather died of it. So did my next-door neighbor. He would seem engaged with you, then suddenly his face would sag, his eyes would grow vacant, and he wouldn’t know where he was."

Watson starts selling generic Alzheimer's drug - BusinessWeek

Watson starts selling generic Alzheimer's drug - BusinessWeek: "Watson starts selling generic Alzheimer's drug

MORRISTOWN, N.J.
Watson Pharmaceuticals Inc. said Thursday it began selling a generic version of Novartis AG's Alzheimer's disease drug Exelon"

Predicting Alzheimer's: PET Scan Plus Memory Test Works Best

Predicting Alzheimer's: PET Scan Plus Memory Test Works Best: "Predicting Alzheimer's: PET Scan Plus Memory Test Works Best
Combination of Brain Scans and Word-Recall Test Best for Predicting Dementia, but It's Expensive"

Exercise may help lower the risk of Alzheimer's | SCNow

Exercise may help lower the risk of Alzheimer's SCNow: "Exercise may help lower the risk of Alzheimer’s
By Nicole Boone WBTW News13 Anchor
Published: July 1, 2010
NEW YORK - It’s believed exercise can lower the risk of Alzheimer’s and a new study suggests the earlier the better."

A little about me

EXPERIENCE


State of Idaho Department of Health and Welfare Family and Children’s Services: (July 93-current date+  July 1, 2010)

► Subject Matter Expert: Developmental Disabilities

► Expert/Instructor: Plan, Goal, and Objective writing

► Expert/Instructor: Community Collaboration

► Early Intervention Specialist

► Appointed: Governor’s Coordinating Council for Families and Children. Member Executive Committee

► Program Manager

► Child Protection supervisor

► Children’s Mental Health supervisor



Rogers Counseling Center: (Feb. 1991-June 1993)

► Psychotherapist: Children and Families

► Director: Children’s Crisis Team

► MANDT (crisis intervention) instructor



State of Utah: Self-Sufficiency Counselor (for adults with disabilities)

(There were a number of articles written in the Deseret News and a national publication on my work and program.)



Additional Experience

► Chair: North West Regional Summit on Youth

► Chair: Madison County Community Council

► Chair: Lewis Clark Coalition for Families and Youth

► Chair: Upper Valley Center for Domestic Violence

► Organizer: July 4th Open Air Concert in Provo Utah (some time in the 1980’s)

► Manager: Festival of the Arts Ball (BYU, also some time in the 80’s)



EDUCATION

Brigham Young University: M.Ed. Educational Psychology, (Aug. 1990)



Additional Education

Ricks College

Seattle Pacific University

Eastern Washington University