Distrusting and Cynical? You May be Hurting Your Brain: Dementia Linked to Cynical Distrust

Distrusting and Cynical? You May be Hurting Your Brain: Dementia Linked to Cynical Distrust: Cynical distrust is defined as the belief that others are mainly motivated by selfish concerns. It's actually been associated with other health problems in the past, such as heart disease. That's why scientists decided to take a closer look at cynical distrust and see how else it might impact an individual.

Are You a Cynic? The Unexpected Way It Could Affect Your Health | TheBlaze.com

Are You a Cynic? The Unexpected Way It Could Affect Your Health | TheBlaze.com: The study, published the American Academy of Neurology’s journal “Neurology,” is the first to examine the relationship between cynical distrust, a belief that others are motivated by selfish concerns, and dementia. Previous research has looked at the link between such an attitude and other health issues.

Workplace Solvents Linked to Long-Term Memory, Thinking Problems – WebMD

Workplace Solvents Linked to Long-Term Memory, Thinking Problems – WebMD: A new study of French power company retirees finds that those who were exposed to solvents and benzene on the job -- even decades earlier -- were more likely to score poorly on memory and thinking tests.

The findings don't directly confirm that the chemicals harmed the mental powers of the former workers, and it was not clear if those with more thinking problems face more issues getting through their day-to-day lives.

Common antidepressant may halt plaque growth associated with Alzheimer’s | Fox News

Common antidepressant may halt plaque growth associated with Alzheimer’s | Fox News: New research published in the journal Science Translational Medicine reveals that the frequently prescribed antidepressant citalopram, also known as Celexa, could play a role in halting the progression of the brain-wasting disease.






ADVERTISEMENT





Antidepressants like citalopram offer hope by targeting the brain’s amyloid beta proteins, which seem to be responsible for triggering the plaque build-up associated with the decline of memory and cognitive function in Alzheimer’s patients.

Alzheimer's disease could be as much about lifestyle as aging : Wsj

Alzheimer's disease could be as much about lifestyle as aging : Wsj: Obesity, smoking, stress and other factors may have as much to do with getting Alzheimer’s as aging does, said Dr. Mark Sager, longtime director of WRAP until he retired last month.

“What we view as a disease of old age is actually a disease of lifestyle and environment to some extent,” Sager said.

A University of California-San Francisco study in 2011 found that seven factors — diabetes, high blood pressure, obesity, smoking, depression, physical inactivity and low educational attainment — contribute to up to half of Alzheimer’s cases.

The seven stages of Alzheimer’s disease progression - Thegardenisland.com: Opinion

The seven stages of Alzheimer’s disease progression - Thegardenisland.com: Opinion: In the early stages of Alzheimer’s disease there is no memory loss and a medical professional would not note any dementia. In the second stage of the disease, the individual may feel that they are having memory issues. They may forget familiar words or where they put something, but a medical examination would not reveal anything, and family and acquaintances would not notice any signs of dementia.

Dad With Alzheimer's Gets His Speech Back When He Sees His Dog

Dad With Alzheimer's Gets His Speech Back When He Sees His Dog: Late-stage Alzheimer's disease can be a cruel and brutal thing, as the loss of vocabulary gives way to the inability to speak at all. That's the situation Lisa Abeyta's father finds himself in most days, but there's one thing that seems to help: the family dog.

Abeyta caught this video of her dad getting his speech back for a rare moment, to tell the dog, "Why don't I take care? I'll take you, and you take me."

New approach to Alzheimer's treatment found in novel class of compounds - Medical News Today

New approach to Alzheimer's treatment found in novel class of compounds - Medical News Today: Researchers publishing in the journal Nature Chemical Biology have described a new class of compounds, called "pharmacologic chaperones," which could aid in a completely new approach to how Alzheimer's disease is treated.

The team explains that a so-called retromer protein complex plays an important part in neurons by steering away amyloid precursor protein (APP) from a part of the cell where it is split, creating amyloid-beta - a potentially toxic byproduct regarded as a hallmark of Alzheimer's.

Young blood reverses some impacts of aging in mice - Technology & Science - CBC News

Young blood reverses some impacts of aging in mice - Technology & Science - CBC News: In a paper published in Nature Medicine, biologists led by Tony Wyss-Coray of Stanford University and Saul Villeda of the University of California San Francisco described two ways of exposing old mice to young blood. They either injected plasma from 3-month-old mice (young adults) into 18-month olds, which are near the end of their lifespan, or surgically connected the circulatory system of a young mouse to that of an old one.

A major advance in understanding Alzheimer's disease

A major advance in understanding Alzheimer's disease: We introduce first a fairly large protein molecule with the horrendous name “repressor element 1 silencing transcription factor” -- thankfully abbreviated REST. I think most of us have wondered how some persons retain their mental capacities for decades after their peers have succumbed to dementia. We tended to think maybe they did not develop plaques, etc. But researchers have had a deeper version of the question: How is it that some aged persons have all the usual molecular components of AD but still retain full cognitive function? It appears that REST just may be the answer.

In young persons, REST is produced in low levels. But as we move into maturity and advanced age, the genes producing REST become more active, making REST as a protective factor for the neurons (brain cells). We have identified a number of genes that normally kill off aging cells that are losing their function (call these cell killers), and we know others that become active in the progression of AD. REST counters both these processes to protect the neurons.

Finding May Explain Why Women More Likely Develop Alzheimer's | Science/AAAS | News

Finding May Explain Why Women More Likely Develop Alzheimer's | Science/AAAS | News: Scientists haven’t pinpointed a definitive cause for Alzheimer’s disease—a fatal brain disorder that robs people of their memory and cognitive abilities. But now researchers have uncovered an intriguing clue about why more women than men develop the condition. A particular gene variant, found in a quarter of the population and long known to raise people’s risk for the disease, seems less menacing in men, new research shows. The findings could have implications for potential gender-specific treatments, some Alzheimer’s investigators suggest

Sun News : Scientists reverse memory loss in mice with Alzheimer's

Sun News : Scientists reverse memory loss in mice with Alzheimer's: Spanish researchers have developed a gene therapy that reverses memory loss in mice in the initial stages of Alzheimer's disease.

The therapy consists of injecting a gene into the brain that causes the production of a protein called Crtc1, which is blocked in patients with the disease. The gene is injected into the hippocampus, a region of the brain essential to memory processing.

Laughter may be the best medicine for age-related memory loss - Medical News Today

Laughter may be the best medicine for age-related memory loss - Medical News Today: We are all familiar with the saying, "laughter is the best medicine." And this motto may ring true when it comes to tackling age-related memory loss; a new study from Loma Linda University in California finds that humor may reduce brain damage caused by the "stress hormone" cortisol, which in turn, improves memory.