New approach to Alzheimer's treatment found in novel class of compounds - Medical News Today: Researchers publishing in the journal Nature Chemical Biology have described a new class of compounds, called "pharmacologic chaperones," which could aid in a completely new approach to how Alzheimer's disease is treated.
The team explains that a so-called retromer protein complex plays an important part in neurons by steering away amyloid precursor protein (APP) from a part of the cell where it is split, creating amyloid-beta - a potentially toxic byproduct regarded as a hallmark of Alzheimer's.
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